The BCM-HGSC sequenced the honey bee, Apis mellifera. The latest version, the Amel_4.5 assembly, is available in GenBank. The version 4.0 assembly was published in October 2006.
The honey bee is important in the agricultural community as a producer of honey and as a facilitator of pollination. It is a model organism for studying the following human health issues: immunity, allergic reaction, antibiotic resistance, development, mental health, longevity and diseases of the X chromosome. In addition, biologists are interested in the honey bee's social organization and behavioral traits.
Sequencing of the honey bee is jointly funded by National Human Genome Research Institute (NHGRI) and the Department of Agriculture (USDA). Multiple drones from the same queen (strain DH4) were obtained from Danny Weaver of B. Weaver Apiaries.
All libraries were made from DNA isolated from these drones. The honey bee BAC library (CHORI-224) was prepared by Pieter de Jong and Katzutoyo Osoegawa at the Children's Hospital Oakland Research Institute.
Publications include a main paper in Nature and up to forty companion papers in Genome Research and Insect Molecular Biology. The BCM-HGSC intends to publish the analysis of the improved genome assembly.